It seems that since the last expl3 update (March 14, 2013), the flexisym package (used by breqn) is no longer compatible with the AMS document classes. Here is a minimal failing example:
\documentclass{amsart}
\usepackage{flexisym}
\begin{document}
\end{document}
This gives two Undefined control sequence errors at \begin{document}. Anyone have any idea what's going on?
flexisymv0.97c, dated March 16, 2013, on MiKTeX since March 18. – Ari Brodsky Mar 19 at 7:09