I'm not sure this is what your looking for, but probably you want something like this:
\documentclass{standalone}
\usepackage{tikz}
\usetikzlibrary{arrows}
\begin{document}
\newcommand{\xangle}{10}
\newcommand{\yangle}{110}
\newcommand{\zangle}{45}
\newcommand{\xlength}{1}
\newcommand{\ylength}{1.7}
\newcommand{\zlength}{0.6}
\pgfmathsetmacro{\xx}{\xlength*cos(\xangle)}
\pgfmathsetmacro{\xy}{\xlength*sin(\xangle)}
\pgfmathsetmacro{\yx}{\ylength*cos(\yangle)}
\pgfmathsetmacro{\yy}{\ylength*sin(\yangle)}
\pgfmathsetmacro{\zx}{\zlength*cos(\zangle)}
\pgfmathsetmacro{\zy}{\zlength*sin(\zangle)}
\begin{tikzpicture}
[ x={(\xx cm,\xy cm)},
y={(\yx cm,\yy cm)},
z={(\zx cm,\zy cm)},
]
\draw[-latex,red] (-1,0,0) -- (3.5,0,0) node[label=\xangle:x] {};
\draw[-latex,blue] (0,-1,0) -- (0,3.5,0) node[label=\yangle:y] {};
\draw[-latex,black] (0,0,-1) -- (0,0,3.5) node[label=\zangle:z] {};
\foreach \c in {-1,...,3}
{ \fill[red] (\c,0,0) circle (0.05cm);
\fill[blue] (0,\c,0) circle (0.05cm);
\fill[black] (0,0,\c) circle (0.05cm);
}
\end{tikzpicture}
\end{document}

You can specify all axes as x={(x-component,y-component)}. In this example you can specify the angle in which a coordinate axis points (xangle) and it's length (xlength). From this, the components are automatically computed. In the options for the TikZ picture I wrote \xx cm, otherwise TikZ will assume the measures are given in points, thus resulting in a very tiny picture. Try playing around with the xyzangles and xyzlengths to see the picture change.