You could produce very neat document using Minion Pro and Myriad Pro (for sans serif) through XeLaTeX. This doesn't affect the main structure of your Latex file. Here is an example of a preamble that you can use:
\documentclass[11pt]{article}
\usepackage{xltxtra}
%\usepackage{sectsty}
\usepackage[parfill]{parskip}
\usepackage[english]{babel}
\usepackage{graphicx}
\usepackage[usenames,dvipsnames]{color}
\usepackage[margin=4cm]{geometry}
\usepackage[autostyle]{csquotes}
%\usepackage[style=authoryear-comp,backref=true]{biblatex}
%\bibliography{refs}
\def\myauthor{...}
\def\mytitle{...}
\def\mycopyright{\myauthor}
\def\mykeywords{...}
\setmainfont[Mapping={tex-text},Numbers={OldStyle},Ligatures={Common}]{Minion Pro}
\setsansfont[Mapping={tex-text},Scale=0.9]{Myriad Pro}
\setmonofont[Mapping=tex-text,Colour=AA0000,Scale=0.9]{Inconsolata}
\title{\mytitle}
\author{\myauthor}
\begin{document}
\maketitle
text here
\end{document}
To compile, you just have to run xelatex on it.
MinionPro. – Philipp Dec 23 '10 at 0:06