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Originally I had a file audio.mp4 that I wanted to play by \href{run:audio.mp4}{START} from a beamer presentation pdf that is run in Preview. Following hints here, I created a .app by appify, and it works: entering open runit.app at the terminal prompt now runs the audio fine. However, \href{run:runit.app}{START} still doesn't work (I tried all minor syntactic variants, with absolute path, ./runit.app, \href[]{ and so forth).

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closed as off topic by Stephan Lehmke, egreg, Martin Schröder, percusse, Kurt Dec 1 '12 at 23:52

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Welcome to TeX.sx! A tip: You can use backticks ` to mark your inline code as I did in my edit. – Corentin Oct 16 '12 at 16:23
Two things to check: If you double click on runnit.app in Finder, does the app work and play the audio file? Second, you need to open the PDF file with a reader such as Acrobat that supports click able links for external applications. I don't think Preview supports this. – Peter Grill Oct 16 '12 at 18:57
Dear Peter, runit.app will start fine from Finder. My primary interest is running audio from Preview, I'm not ready to install Acrobat for security/bloat reasons. Since media9 and other packages seem to have the same limitation, I'm more or less ready to give up on this and suffer the indignity of pushing an external button during my presentation. Thanks anyway, learning about appify was worth it in and of itself. – Noob Oct 18 '12 at 14:03