The following example defines \Cdot to generate a larger dot. It takes an optional argument with a scaling factor. The default is 1.25.
The centered dot remains centered after scaling by moving the dot to the baseline
before scaling. The depth that is caused by scaling is removed. Exceeded height is truncated to the height of \bullet.
The width is more difficult. The exact values of the side bearings are unknown.
For small scaling factors, the original width might be a good choice. That is
implemented in the example below. For larger scaling factors the width might be increased by a smaller scaling factor. At any case, the horizontal and vertical scaling factors of the glyph must be the same, otherwise the glyph looses the circle shape.
The example file:
\documentclass{article}
\usepackage{graphicx}
\usepackage{amstext}
\newcommand*{\Cdot}[1][1.25]{%
\mathpalette{\CdotAux{#1}}\cdot%
}
\newdimen\CdotAxis
\newcommand*{\CdotAux}[3]{%
{%
\settoheight\CdotAxis{$#2\vcenter{}$}%
\sbox0{%
\raisebox\CdotAxis{%
\scalebox{#1}{%
\raisebox{-\CdotAxis}{%
$\mathsurround=0pt #2#3$%
}%
}%
}%
}%
% Remove depth that arises from scaling.
\dp0=0pt %
% Decrease scaled height.
\sbox2{$#2\bullet$}%
\ifdim\ht2<\ht0 %
\ht0=\ht2 %
\fi
% Use the same width as the original \cdot.
\sbox2{$\mathsurround=0pt #2#3$}%
\hbox to \wd2{\hss\usebox{0}\hss}%
}%
}
\newcommand*{\test}[1]{%
\text{%
\setlength{\fboxsep}{0pt}%
\setlength{\fboxrule}{.1pt}%
\fbox{$#1$}%
}%
}
\begin{document}
$x_{i\cdot} = x_{i\test{\cdot}} = \sum_{j} x_{ij}$
$x_{i\Cdot} = x_{i\test{\Cdot}} = \sum_{j} x_{ij}$
$x_{i\Cdot[1.5]} = x_{i\test{\Cdot[1.5]}} = \sum_{j} x_{ij}$
$x_{i\Cdot[1.75]} = x_{i\test{\Cdot[1.75]}} = \sum_{j} x_{ij}$
$x_{i\Cdot[2]} = x_{i\test{\Cdot[2]}} = \sum_{j} x_{ij}$
\end{document}

\bulletfor such occasions but it's a matter of taste ;) – percusse Nov 7 '12 at 3:00