Here is a minimal example.
Consider the document
\documentclass{article}
\begin{document}
Hello world!
\end{document}
This compiles perfectly. However, if I include an unfamiliar package, as follows:
\documentclass{article}
\usepackage{mathdesign}
\begin{document}
Hello world!
New text to be shown in next build
\end{document}
then, the document compiles with "0 Error(s), 0 Warning(s), 0 Bad Box(es), 0 Page(s)" and just displays the previous build of the document, without the "New text to be shown in next build" added.
I am using TeXnicCenter and MikTeX 2.9. The "install missing packages on the fly" option has always behaved funnily in my setup.