To test Mico's upcoming selnolig package, I tried out LuaLaTeX. While the overall experience for me as a pdfLaTeX end-user was very similar, I noticed that LuaLaTeX takes a long time to load fonts. ...
I have some opentype fonts (otf) which I use with fontspec. Everything works fine. During the compilation LuaLaTeX load the otf-files in a temporary file. For example: (load: ...