As of 2021, this question could use an update. In PDFTeX, the Culmus Project fonts are now available for 8-bit LaTeX, through the culmus-latex
package.
\documentclass{article}
\usepackage{amsmath,amssymb}
% The culmus-latex package is available for free at:
% https://sourceforge.net/projects/ivritex/files/culmus-latex/
\usepackage{culmus}
% Use Frank Ruehl CLM as a math symbol font:
\DeclareSymbolFont{alephbet}{HE8}{frank}{m}{n}
\SetSymbolFont{alephbet}{bold}{HE8}{frank}{b}{n}
% remove the definitions from amssymb
\let\aleph\relax\let\beth\relax
\let\gimel\relax\let\daleth\relax
\DeclareMathSymbol{\aleph}{\mathord}{alephbet}{"E0}
\DeclareMathSymbol{\beth}{\mathord}{alephbet}{"E1}
\DeclareMathSymbol{\gimel}{\mathord}{alephbet}{"E2}
\DeclareMathSymbol{\daleth}{\mathord}{alephbet}{"E3}
\DeclareMathSymbol{\he}{\mathord}{alephbet}{"E4}
\DeclareMathSymbol{\vav}{\mathord}{alephbet}{"E5}
\DeclareMathSymbol{\zayin}{\mathord}{alephbet}{"E6}
\DeclareMathSymbol{\het}{\mathord}{alephbet}{"E7}
\DeclareMathSymbol{\tet}{\mathord}{alephbet}{"E8}
\DeclareMathSymbol{\yod}{\mathord}{alephbet}{"E9}
\DeclareMathSymbol{\kaf}{\mathord}{alephbet}{"EB}
\DeclareMathSymbol{\lamed}{\mathord}{alephbet}{"EC}
\DeclareMathSymbol{\mem}{\mathord}{alephbet}{"EE}
\DeclareMathSymbol{\nun}{\mathord}{alephbet}{"F0}
\DeclareMathSymbol{\samech}{\mathord}{alephbet}{"F1}
\DeclareMathSymbol{\ayin}{\mathord}{alephbet}{"F2}
\DeclareMathSymbol{\pe}{\mathord}{alephbet}{"F4}
\DeclareMathSymbol{\tsadi}{\mathord}{alephbet}{"F6}
\DeclareMathSymbol{\qof}{\mathord}{alephbet}{"F7}
\DeclareMathSymbol{\resh}{\mathord}{alephbet}{"F8}
\DeclareMathSymbol{\shin}{\mathord}{alephbet}{"F9}
\DeclareMathSymbol{\tav}{\mathord}{alephbet}{"FA}
\begin{document}
Now I can use $A_\shin$, $\shin$ or $B^\shin$.
{\bfseries\boldmath Also, $A_\shin$, $\shin$ or $B^\shin$.}
$X\aleph\beth\gimel\daleth\he\vav\zayin\het\tet\yod\kaf\lamed\mem\nun\samech\ayin\pe\tsadi\qof\resh\shin\tav X$
\end{document}

To install the package, decompress the files to your local TeX tree, then run
texhash
updmap-sys --enable Map=culmus.map
I used Frank Ruehl for this example, but many other fonts are supported.
In LuaLaTeX or XeLaTeX, it is probably more convenient to switch to text mode and use an OpenType font. (Although it is also possible to declare Hebrew letters from a Unicode-encoded symbol font.) In this example, I use Libertinus Serif with Libertinus Math:
\documentclass{article}
\usepackage{Libertinus} % For example
\newcommand\vav{\textup{\rmfamily\symbol{"05D5}}} % ו
\newcommand\shin{\textup{\rmfamily\symbol{"05E9}}} % ש
\begin{document}
\section*{The Symbol \(\shin\)}
\( f(t) \cdot \shin \)
\end{document}

The hex codes here are the Unicode codepoints of the Hebrew letters.
You can insert any text-mode commands within \textup
or \textnormal
, including switching to a Hebrew font that you load with fontspec
.
If you need so many symbol alphabets that you’re using Hebrew, you will not run out if you use unicode-math
.
$\aleph$
, that's coming from a TeX maths font (if you are not using unicode maths)...