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I would like to reference the compounds in my schemes with achemso in a manner similar to the options given by chemstyle, but is that possible? The documentation for achemso list a scheme environment but the \schemref macro fails

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The scheme environment has really nothing to do with \schemeref: the naming in chemstyle is just because of the likely use case. In particular, the way that \schemeref works is by using the psfrag package to do search-and-replace in EPS figures.

For achemso, the class is about submission to the ACS. They will need 'final' graphics (they don't use LaTeX for the journal itself) so this kind of auto-replacement is inappropriate. For the achemso package, the code is pretty minimal and you can load chemstyle as well should you wish.

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