I'm using the bioinfo.cls for my paper and the margins are just too wide. The sample pdf file the publication provided doesn't seem to have this problem(named Sample.pdf; the complete template can be found here: https://academic.oup.com/DocumentLibrary/Bioinformatics/cabios-template.zip). However, when I try to compile the main.tex file, I get margins that are too wide. I tried using the using the geometry package, but the margins are even worse with it.
All the files are accessible at this Sharelatex project: https://www.sharelatex.com/project/5887a3ff3cc6276117061161