I don’t know of any handwritten font specifically designed for math, or legacy LaTeX encodings. However, the unicode-math
project lets you mix and match any OpenType and TrueType fonts.
Here, I’ve kitbashed the letters from VAG Handwritten and filled in numbers and some math symbols from Tillana. Any symbols not in these fall back to GFS Neohellenic Math.
\documentclass{article}
\usepackage[math-style=upright]{unicode-math}
\defaultfontfeatures{Scale=MatchLowercase}
% Tillana is a free font by the Indian Type Foundry, available at:
% https://github.com/itfoundry/tillana/
% VAG Handwritten is a free font by VAG Design, available at:
% https://www.fontsquirrel.com/fonts/VAG-HandWritten
\setmainfont{VAG-HandWritten.otf}
\setmathfont{GFS Neohellenic Math}
\setmathfont[range={"03C0, "2013-"2014, "2018-"201A, "201C-"201E, "2021-"2022,
"2026, "2030, "2039-"203A, "2044, "20AC, "20BA, "20BD,
"2113, "2122, "2126, "212E, "2202, "2206, "220F, "2211,
"2212, "2215, "221A, "221E, "222B, "2246, "2260, "2264,
"2265, "25CA}
]{Tillana-Regular.ttf}
\setmathfont[range=bfup/{Latin,latin,num}
]{Tillana-Semibold.ttf}
\setmathfont[range={"00-"FF,
up/{Latin,latin,Greek,greek},
\increment}
]{VAG-HandWritten.otf}
\setmathfont[range=up/num
]{Tillana-Regular.ttf}
\begin{document}
\[ \lim_{t \to \infty} \frac{\partial}{\partial t}
\int_0^{2 \muppi} \frac{t^2}{2} \mathop{\symup{d}t} \leq
\sum_{i=1}^N \frac{\muppi i}{\sqrt 2} \approx \increment \symbfup{v}t \]
\[ \frac{\sin \theta}{\Theta} =
\frac{\sin \varphi}{\Phi} =
\frac{\sin \gamma}{\Gamma} \]
\end{document}

The widely-available handwritten font with the biggest repertoire of symbols is—you might want to sit down for this, don’t get mad at me, I’m just the messenger—Comic Sans. And some physicists do use it for their presentation slides. You might also have a look at Pecita. But you can sub in any handwritten Greek font of your choice with a command like
\setmathfont[range=up/{Latin,latin,Greek,greek,num}]{Some Font}