Not knowing how wide the text block of your document is, I don't think it's possible to give a completely general or automatic method for achieving the look-and-feel you illustrate in your example. However, as the MWE below suggests, using the split
environment provided by the amsmath
package inside an equation
environment would seem to come reasonably close to having a fully-automated method.
Relative to the visual example you provide, this method has the advantage (in my opinion...) of letting you align the +
signs across all four lines of the equation. Note also that because the split
environment doesn't provide its own numbering of equation lines, the output automatically has only one equation number that's correctly centered vertically between lines 2 and 3 of the equation.
\documentclass{article}
\usepackage{amsmath}
\begin{document}
\begin{equation}
\begin{split}
a_1+b_1+c_1+d_1+{}&e_1+f_1 \\
&g_1+h_1+i_1+j_1+k_1+l_1 \\
a_2+b_2+c_2+d_2+{}&e_2+f_2 \\
&g_2+h_2+i_2+j_2+k_2+l_2
\end{split}
\end{equation}
\end{document}

Observe that it's necessary, in lines 1 and 3 of the equation's code, to place a {}
construct before the &
alignment points so that TeX doesn't think that the preceding +
symbol is a unary operator.
mathtools
package provides amultlined
environment that might fit your needs. Maybe this question can help. – egreg Jun 1 '12 at 16:25