You can use stacked plots to draw the uncertainty bands before plotting the actual data line. First you'd say \addplot table [y expr=\thisrow{<data col>}-\thisrow{<error col}] {<datatable>};
to determine the lower bound, and then
\addplot [fill=<colour>] table [y expr=2*\thisrow{<error col}] {<datatable>} \closedcycle;
to fill the area between the lower and upper bound.
These two \addplot
commands can be wrapped in a macro to generate the plots, as follows:
\newcommand{\errorband}[5][]{ % x column, y column, error column, optional argument for setting style of the area plot
\pgfplotstableread[col sep=comma, skip first n=2]{#2}\datatable
% Lower bound (invisible plot)
\addplot [draw=none, stack plots=y, forget plot] table [
x={#3},
y expr=\thisrow{#4}-\thisrow{#5}
] {\datatable};
% Stack twice the error, draw as area plot
\addplot [draw=none, fill=gray!40, stack plots=y, area legend, #1] table [
x={#3},
y expr=2*\thisrow{#5}
] {\datatable} \closedcycle;
% Reset stack using invisible plot
\addplot [forget plot, stack plots=y,draw=none] table [x={#3}, y expr=-(\thisrow{#4}+\thisrow{#5})] {\datatable};
}
you can generate a plot with an error band using
\errorband[<plot options>]{<data file>}{<x column>}{<y column>}{<error column>}
Below is an example plotting the Average Northern and Soutern sea ice extent.
Fetterer, F., K. Knowles, W. Meier, M. Savoie, and A. K. Windnagel. 2017, updated daily. Sea Ice Index, Version 3. [Data/North+South/Month]. Boulder, Colorado USA. NSIDC: National Snow and Ice Data Center. doi: https://doi.org/10.7265/N5K072F8.

\documentclass{article}
\usepackage{pgfplots, pgfplotstable}
\begin{document}
\newcommand{\errorband}[5][]{ % x column, y column, error column, optional argument for setting style of the area plot
\pgfplotstableread[col sep=comma, skip first n=2]{#2}\datatable
% Lower bound (invisible plot)
\addplot [draw=none, stack plots=y, forget plot] table [
x={#3},
y expr=\thisrow{#4}-2*\thisrow{#5}
] {\datatable};
% Stack twice the error, draw as area plot
\addplot [draw=none, fill=gray!40, stack plots=y, area legend, #1] table [
x={#3},
y expr=4*\thisrow{#5}
] {\datatable} \closedcycle;
% Reset stack using invisible plot
\addplot [forget plot, stack plots=y,draw=none] table [x={#3}, y expr=-(\thisrow{#4}+2*\thisrow{#5})] {\datatable};
}
\begin{tikzpicture}
\begin{axis}[
compat=1.5.1,
no markers,
enlarge x limits=false,
ymin=0,
xlabel=Day of the Year,
ylabel=Sea Ice Extent\quad/\quad $10^6\,\mathrm{km}^2$,
legend entries={
$\pm$ 2 Standard Deviation,
NH 1997 to 2000 Average,
$\pm$ 2 Standard Deviation,
SH 1997 to 2000 Average,
NH 2012,
SH 2012
},
legend reversed,
legend pos=outer north east,
legend cell align=left,
x post scale=1.2
]
% Northern Hemisphere Average
\errorband[orange, opacity=0.5]{NH_seaice_extent_climatology_1979-2000.csv}{0}{3}{4}
% Northern Hemisphere 2012
\addplot [thick, orange!50!black] table [
x index=0,
y index=3,
skip first n=2,
col sep=comma,
] {NH_seaice_extent_climatology_1979-2000.csv};
% Southern Hemisphere Average
\errorband[cyan, opacity=0.5]{SH_seaice_extent_climatology_1979-2000.csv}{0}{3}{4}
% Southern Hemisphere 2012
\addplot [thick, cyan!50!black] table [
x index=0,
y index=3,
skip first n=2,
col sep=comma,
] {SH_seaice_extent_climatology_1979-2000.csv};
\addplot [ultra thick,red] table [
col sep=comma,
skip first n=367,
x expr=\coordindex,
y index=3
] {NH_seaice_extent_nrt.csv};
\addplot [ultra thick,blue] table [
col sep=comma,
skip first n=367,
x expr=\coordindex,
y index=3
] {SH_seaice_extent_nrt.csv};
%
\end{axis}
\end{tikzpicture}
\end{document}
UPDATE
The currently available data covers the average extent of sea ice from 1981 to 2010. For reproducibility, the LaTeX code can be updated as follows (excluding the NH and SH 2012 lineplots):
$\pm$ 2 Standard Deviation,
NH 1981 to 2010 Average,
$\pm$ 2 Standard Deviation,
SH 1981 to 2010 Average
},
legend reversed,
legend pos=outer north east,
legend cell align=left,
x post scale=1.2
]
% Northern Hemisphere Average
\errorband[orange, opacity=0.5]{N_seaice_extent_climatology_1981-2010_v3.0.csv}{0}{1}{2}
% Northern Hemisphere 2012
\addplot [thick, orange!50!black] table [
x index=0,
y index=1,
skip first n=2,
col sep=comma,
] {fig/north.csv};
% Southern Hemisphere Average
% \errorband[<plot options>]{<data file>}{<x column>}{<y column>}{<error column>}
\errorband[cyan, opacity=0.5]{S_seaice_extent_climatology_1981-2010_v3.0.csv}{0}{1}{2}
% Southern Hemisphere 2012
\addplot [thick, cyan!50!black] table [
x index=0,
y index=1,
skip first n=2,
col sep=comma,
] {S_seaice_extent_climatology_1981-2010_v3.0.csv};